What is Melatonin?
Melatonin is a hormone produced in the pineal gland from serotonin. Melatonin plays a key role in the synchronization of hormones involved in maintaining
normal 'circadian' or daily rhythm. The release of melatonin is stimulated by darkness and suppressed by light via neuroendocrine communication between the pineal gland and the retina. The secretion of melatonin increases when daylight hours are reduced (winter) and decreases when daylight hours are extended (summer). This phase shift maintains a normal circadian pattern in individuals throughout the year.
What are the Possible Benefits of Melatonin?
The main clinical applications of melatonin are:
- Jet lag. The best way to reduce effects of jet lag was shown in a double blind, placebo-controlled trial with the administration of 5mg of melatonin in the evening at the new destination for a duration of 5 days (Petrie et al., 1993)
- Insomnia. Melatonin is a potent inducer of sleep but only in individuals with low melatonin levels. As melatonin output decreases with age, supplementation with 3mg one hour before retiring is often found to be beneficial.
Who Can Benefit from Melatonin?
Melatonin can be helpful for those who plan to travel, as well as, people suffering from difficulty sleeping.
How Should I Take Melatonin?
Take exactly as recommended by your doctor. Do not take larger or smaller amounts or for longer than recommended. Melatonin is typically taken daily 1/2 hour to 1 hour before bedtime.
What are the Possible Side Effects of Melatonin?
What Should I Avoid When Taking Melatonin?
- Melatonin may have sedating effects and is for bedtime use only.
Melatonin may be contraindicated in:
- Seasonal affective disorder
- Autoimmune disease
- MAO inhibitors
Serving Size: 1 Capsule
Servings Per Container: 60
|Amount Per Serving % Daily Value
|Melatonin (99.5% pure synthetic melatonin) 3 mg *
Other ingredients: hypo-allergenic plant fiber, vegetable capsule
*daily value not established
DISCLAIMER * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.