Finding a New Way to Support Weight Loss
If you have ever felt like you are doing everything right by eating better, moving more, and getting enough rest, but the scale still will not move, you are not alone. Weight loss can be complicated. Hormones, metabolism, inflammation, and even stress can all affect how your body responds.
That is why our providers sometimes recommend a treatment called Low Dose Naltrexone (LDN). Under medical supervision, LDN may help your body restore balance, reduce cravings, and make it easier to stay consistent with your healthy habits.
At Valley Medical Weight Loss & Med Spa, our goal is to blend trusted science with compassionate care. We help you find what truly works for your body and lifestyle.
What is Low Dose Naltrexone (LDN)?
LDN is a smaller, customized version of a medication that has been approved by the FDA for alcohol and opioid dependence at much higher doses. When prescribed in very low doses, usually between 1 and 6 milligrams, it works differently in the body.
At low doses, LDN briefly blocks specific receptors in the brain that interact with the body’s natural endorphins, also known as the “feel-good” chemicals. When this temporary block ends, the body responds by increasing its own production of endorphins. These endorphins affect mood, energy, inflammation, and appetite regulation.
In simple terms, LDN can help your body reset some of the natural signals that influence cravings, energy levels, and metabolism (Drugs.com LDN Overview, LDN Research Trust).
How LDN May Support Weight Management
Weight management involves more than just eating less and moving more. For many patients, internal factors such as inflammation, hormonal imbalance, and brain chemistry play a significant role.
LDN is not a stand-alone solution for weight loss, but it can support the process for people who struggle with:
- Persistent cravings for sugar, snacks, or carbohydrates
- Emotional eating or stress-related eating habits
- Weight plateaus despite consistent diet and activity
- Low energy or slower metabolism
LDN may support weight management in several ways:
- Improving endorphin balance. A better balance of natural endorphins can lead to improved mood, focus, and motivation to stay on track.
- Reducing appetite and cravings. Opioid receptors are part of the brain’s reward system that makes food taste especially satisfying. Temporary receptor blocking can make cravings less intense (PubMed Study).
- Supporting metabolism. By reducing inflammation and improving insulin sensitivity, LDN may help your metabolism operate more efficiently.
- Reducing inflammation. Chronic inflammation can slow weight loss. LDN may help calm that process so the body can better focus on balance and repair.
Every person is different. Some patients notice reduced cravings and improved energy within four to eight weeks. For others, changes happen gradually over time (Clearspring Compounding LDN Overview)
How LDN Fits into Your Weight Loss Program
At Valley Medical Weight Loss & Med Spa, all programs begin with a medical evaluation. Your provider reviews your health history, lab results, and goals to build a personalized plan.
If LDN is appropriate, here is what you can expect:
- Start low. Most patients begin around 1.125 milligrams at bedtime. The dose is increased slowly as tolerated.
- Monitor progress. You and your provider will talk about changes in appetite, energy, or sleep.
- Combine with lifestyle habits. LDN works best when paired with healthy nutrition, consistent physical activity, and proper sleep.
- Reevaluate regularly. Around the twelve-week mark, you and your provider will decide together whether to continue.
There are no contracts or long-term commitments. Your plan is flexible, transparent, and focused on your needs.
What You Might Notice
Many patients describe small but positive shifts such as:
- Less snacking or emotional eating
- Fewer cravings for sweets or carbohydrates
- More consistent energy throughout the day
- Better focus and motivation to stay on track
These changes can help build momentum. With regular provider check-ins and supportive guidance, LDN may make it easier to follow through on healthy habits and support long-term progress.
Safety and Possible Side Effects
LDN is generally well tolerated, but like any medication, it can cause temporary side effects. Some patients experience:
- Vivid dreams or sleep changes, which often improve within a few weeks
- Mild nausea or upset stomach
- Temporary headache or fatigue
- Short-term restlessness or irritability
If you experience side effects, your provider can adjust your dose or timing. Taking LDN at bedtime often helps minimize discomfort.
LDN should not be used if you are:
- Currently taking opioid pain medications
- Pregnant or breastfeeding
- Diagnosed with significant liver impairment
- Receiving chemotherapy or certain immune-suppressing treatments
Because LDN is prescribed off-label for weight management, it should only be used under physician supervision.
How Long It Takes to See Results
LDN works slowly and steadily. Because it influences the body’s natural processes, most patients begin evaluating progress around eight to twelve weeks.
During that time, your provider looks at more than the number on the scale. They consider whether you have fewer cravings, improved portion control, and better consistency with your nutrition plan.
Patience matters. These small, steady changes often lead to sustainable results over time (Diet vs Disease LDN Review).
Realistic Expectations
LDN is best used as part of a complete wellness plan. Research suggests that while it may influence appetite and metabolism, it is not a substitute for lifestyle changes. Studies on similar medications show better outcomes when paired with diet and activity (PMC Study).
At Valley Medical, we focus on honesty and transparency. LDN can be a helpful tool, but we will always tailor your plan to what works best for your unique body and lifestyle.
Pricing and Availability
LDN is available through all Valley Medical Weight Loss & Med Spa locations, including Phoenix, Tempe, Glendale, and Chandler.
We keep pricing clear and simple:
- LDN Weekly Combo Pack: $31.95
- 4-Week Supply: $25
- Plus Meds 4-Week Pack: $25
Your provider will review which option best fits your program.
Frequently Asked Questions
How soon will I notice a difference?
Most patients notice subtle improvements within one to two months, such as fewer cravings or steadier energy.
Can I combine LDN with other medications?
In some cases, yes. LDN may be combined under physician supervision with other treatments, such as compounded GLP-1 medications, when medically appropriate.
What if I miss a dose?
Simply take your next scheduled dose. Do not double up. If you stop taking it for a few weeks, your provider may recommend restarting at a lower dose.
Is LDN right for me?
Schedule a consultation. Together we will review your goals, health history, and lab results to determine whether LDN is a good fit for your plan.
Take the Next Step
If you feel stuck in your weight loss journey, LDN may be worth exploring. Schedule your consultation with Valley Medical Weight Loss & Med Spa today. Our providers will take the time to understand your goals and build a plan that supports you every step of the way.
We never require contracts and we focus on one thing: helping you feel and function your best.
Important Information and Disclosures
Educational use only
Low Dose Naltrexone (LDN) has not been approved by the FDA for weight management. This article is for educational purposes and does not replace medical advice.
Medication disclaimer
Compounded medications are available by prescription only. They are not FDA approved and have not been evaluated by the FDA for safety or effectiveness. When prescribed, they are prepared by licensed pharmacies for individual patients in accordance with applicable laws. Individual experiences vary. Use only under the supervision of a licensed medical provider.
General program disclaimer
Valley Medical Weight Loss & Med Spa does not guarantee weight loss outcomes. Programs are medically supervised, but results vary by individual. All treatments require evaluation and prescription by a licensed provider.
