By Dr. Gregory Rich, Valley Medical Weight Loss
One of the first questions patients ask me is, “Am I the right candidate for compounded semaglutide?” It is a fair question, and the answer depends on several factors. Compounded semaglutide can be an important tool for some people, but it is not right for everyone. That is why a medical evaluation is always the first step.
In this article, I will walk you through who may benefit most from compounded semaglutide, who should avoid it, and why physician guidance is critical.
Who May Be a Good Candidate
Compounded semaglutide may be considered for adults who fall into one of two main categories:
- BMI of 30 or higher. This is classified as obesity and often comes with health risks such as diabetes, high blood pressure, or heart disease.
- BMI in the high 20s with health concerns. Patients who are overweight and also have conditions like high cholesterol, prediabetes, or hypertension may also be considered.
In both cases, the goal is not simply cosmetic weight loss. It is about addressing health challenges, reducing risks, and improving quality of life.
When It May Not Be Recommended
There are also situations where compounded semaglutide is not a good fit. Examples include:
- A personal or family history of medullary thyroid carcinoma or MEN2
- A history of pancreatitis
- Certain gallbladder or gastrointestinal issues
During a consultation, I review these factors in detail. Even if a patient is eager to start medication, safety always comes first.
The Patients Who Benefit Most
From my experience, compounded semaglutide is most helpful for patients who:
- Have tried multiple diets and programs over the years
- Lost weight in the past but regained it once the program ended
- Feel stuck in a cycle of hunger, cravings, and frustration
- Want support to finally make lifestyle changes stick
For these patients, compounded semaglutide is not a shortcut. It simply lowers the volume on constant hunger and cravings, which makes it easier to stay consistent with nutrition, activity, and accountability.
Real-Life Example
I often work with patients who feel like they have “tried everything.” One patient had followed strict diets in the past and lost weight quickly, but the moment the program ended, the old habits came back. She described it as feeling like her body was fighting against her.
With compounded semaglutide, she noticed that cravings were no longer overwhelming. That gave her the space to focus on balanced meals, light exercise, and weekly check-ins. Over time, the scale reflected those changes, but more importantly, she said she felt in control of her choices for the first time in years.
This story is common, and it highlights how medication can be part of a much larger support system.
Why Not Everyone Gets a Prescription
At Valley Medical, not every patient leaves with a prescription for compounded semaglutide, and that is intentional. My job as a physician is to recommend what is most appropriate for your health long term.
Sometimes that means starting with compounded semaglutide. Other times, it may mean focusing first on nutrition, vitamin support, or other tools. Patients deserve a plan that fits their needs, not a one-size-fits-all approach.
The Role of Medical Oversight
Even for patients who are good candidates, monitoring is essential. Here is why:
- Adjusting doses. Starting too high or increasing too quickly can lead to side effects. A gradual, physician-guided approach is safer and more tolerable.
- Tracking progress. Weight trends are only part of the picture. I also monitor blood work, energy, sleep, and other markers of health.
- Making changes when needed. If the medication does not feel like the right fit, or if side effects persist, we can make adjustments.
This ongoing partnership between patient and provider makes the process safer and more sustainable.
FAQs Patients Ask About Candidacy
Q: Can I try compounded semaglutide if I only want to lose 10 pounds?
A: In most cases, no. This medication is best suited for patients with obesity or weight-related health conditions.
Q: What if I have diabetes?
A: Compounded semaglutide can influence blood sugar. That is why we review medications, history, and lab results before prescribing.
Q: What if I have had my gallbladder removed?
A: That does not automatically exclude you, but it is important to review your medical history carefully before deciding.
Compounded semaglutide can be a valuable part of a comprehensive weight-management plan, but it is not right for everyone. The best candidates are adults with obesity or weight-related health concerns who are ready to make lifestyle changes alongside medical support.
At Valley Medical, my role is to make sure every patient receives a plan that matches their needs and goals. For some, that may include compounded semaglutide. For others, it may be different tools. Either way, the focus is always on safe, sustainable progress and improved quality of life.
Disclaimer:
Compounded medications, including compounded GLP-1 medications, are available by prescription only. They are not FDA approved and have not been evaluated for safety or effectiveness by the FDA. They are prepared by licensed pharmacies in accordance with state and federal laws. Compounded Semaglutide may be considered when a commercially available alternative is not suitable or available for a specific patient. All treatment decisions are made by a licensed provider. Individual results vary. Always use under the supervision of a licensed medical provider.
