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By: The Hidden Epidemic of Sexual Health and What We Can Do
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Tempe 480.968.5673
Glendale 602.374.3374
Phoenix 602.441.3305
Chandler480.447.1165
Understanding and Addressing Rapid Weight Loss Side Effects The buzz around the weekly weight loss injection Ozempic continues to grow, but a few side effects are causing some to take pause. At the top of this list are Ozempic® butt, Ozempic® face, and Ozempic® body. If you are taking Ozempic®,
The buzz around the weekly weight loss injection Ozempic continues to grow, but a few side effects are causing some to take pause. At the top of this list are Ozempic® butt, Ozempic® face, and Ozempic® body.
If you are taking Ozempic®, Wegovy®, or generic GLP-1 for diabetes or weight loss, the last thing you want is the side effect of loose and wrinkly skin. This rare side effect creates a mix of emotions. The number on the scale is decreasing and clothing fits better, but wrinkly sagging skin can leave you feeling self-conscious.
At Valley Medical Weight Loss and Med Spa across all four Phoenix metro locations, we help individuals prevent and treat skin laxity during rapid weight loss through proactive strategies and advanced aesthetic treatments.
Let’s dive in and discuss what these terms mean, if you are at risk, and what to do if it impacts you.
This refers to the sagging and wrinkled skin that is a rare side effect of any rapid weight loss intervention. Since Ozempic® is more mainstream than other interventions, we hear about it more. However, bariatric surgery patients have the same concern. So do many moms after giving birth and breastfeeding. If you watch shows like The Biggest Loser, it’s something some of the contestants reference.
Where the sagging occurs varies greatly from those it affects, as you can’t pick and choose when, where, and how fast you will lose weight in any area—or if you will develop Ozempic® butt.
Common areas affected:
Through experience at Valley Medical Weight Loss, we’ve observed that proactive treatment during weight loss—not just after—yields the best results for preventing and minimizing skin laxity.
It’s easy to forget, but your skin is your body’s largest organ. It is a protective barrier comprised of proteins, including collagen and elastin.
Collagen and elastin work together to provide your skin’s structure, elasticity, strength, firmness, fullness, moisture, and hydration.
As you gain weight, your skin stretches to accommodate the excess volume. As you lose weight, the skin has less internal tissue to cover. This can make some areas look flat or hollow and can cause sagging.
Unless your collagen and elastin fibers have been damaged, your body can regain much of its elasticity, but it takes time. Either way, the faster you lose weight, the more noticeable the sagging.
In addition to the sagging, skin often looks wrinkly. Since we associate wrinkles with aging, you may feel like you look older than your chronological age. However, the wrinkles caused by Ozempic® butt or body aren’t the same as wrinkles caused by aging or sun exposure.
Think of it a bit more like a deflated balloon. When inflated, the balloon is full and smooth. When deflated it’s smaller than it was before you blew it up but stretched out and wrinkly. The same is true for your skin.
Unlike a balloon, you can actively work to regain elasticity.
There are no guarantees one way or the other, and this side effect is rare. However, there are some factors that will increase the risk of sagging skin.
The more fat you have in any region of your body, the more it increases your odds of sagging. You may have loose skin in several places or just one or two. If you have 100 or more pounds to lose, loose skin is far more likely, but it can occur if you have far less to lose.
The longer you have been obese, the more likely it is that your collagen and elastin have been damaged. Those with 100 or more pounds to lose are at a higher risk for Ozempic® butt or sagging in other areas. However, the longer your skin has been stretched out, the more likely damage has occurred.
As you age, your body produces less collagen and elastin. So even if there is no damage, your skin may not have the regeneration capacity to tighten back up. Women experience accelerated collagen loss during menopause—up to 30% in the first five years.
You’ve likely heard that the sun can prematurely age your skin. This is caused by damaging and slowing down the natural production of collagen and elastin. So, be sure to lather up daily with broad-spectrum UV protection. Reapply every 4 hours when in the sun for extended periods of time. In Arizona’s intense sun, daily SPF 50+ is essential.
How your skin responds to weight loss, and how you age in general, are linked to your individual genetics. There is nothing you can do to change your genetics, but you may be able to stimulate your body’s regeneration process.
Your lifestyle can prematurely age you in a variety of ways. Smoking is at the top of this list as it damages collagen and prematurely slows production. Consistently insufficient sleep and poor overall skincare also contribute to skin health and appearance.
In most cases, Ozempic® butt is primarily a cosmetic concern. However, it can pose some health risks and lifestyle disturbances.
Physical discomfort: Loose skin can get in the way while working out or going about daily life. This may keep you from doing some of the things you love, even things you did before you lost weight.
Mental and emotional: You may worry about other people seeing your loose skin, causing a new body image issue. Although you can fit into smaller clothing, it may limit what you feel comfortable wearing.
Skin conditions: If your skin folds over itself, you are at a higher risk for skin-irritation-related health issues. This includes excessive sweat, fungus, rashes, and ulcers. If not treated promptly these can be painful and lead to severe infections.
Through work at Valley Medical Weight Loss, we provide emotional support and practical solutions to help individuals feel confident throughout their weight loss journey.
Your skin is 80% collagen, so stimulating collagen production may accelerate the rate at which your skin recovers. Even if it isn’t damaged, after drastic weight loss, your collagen is not as strong or healthy as it was before your weight gain.
We take a deep dive into collagen regeneration in this blog post about preventing sagging skin, but below are a few tips to minimize Ozempic® butt:
This includes bone broth, nuts, seeds, legumes, dairy, fish, eggs, chicken, beef, and other foods high in protein. Also, drink plenty of water—aim for 80-100 oz daily for optimal skin hydration.
Key nutrients for collagen:
Consider taking a collagen supplement a few days a week, along with supplements that support collagen or minimize oxidative damage such as vitamin C, zinc, copper, Panax ginseng, omegas, and algae.
Effective supplementation:
Our Pure O.N.E Multivitamin provides many of these essential nutrients for skin health during weight loss.
This includes minimizing alcohol, trans fat, sugar, and caffeine. Also, exercise (especially strength training to build muscle), prioritize quality sleep (7-9 hours nightly), stop smoking, and personalize your whole-body health.
Daily habits that help:
Skip topical collagen creams (molecules are too large to penetrate skin) but apply antioxidant-rich daily moisturizers from head to toe. Don’t forget daily UV protection.
Effective topical ingredients:
Surgery is an option, but it typically isn’t covered by insurance. It also comes with pain and swelling that requires taking a few weeks off from work. If surgery isn’t right for you, there are a variety of non-surgical options to explore.
We will work with you to determine what treatment is appropriate for the area of your body you are experiencing sagging. You may require different treatments for Ozempic® butt and Ozempic® face.
Morpheus8 is a combination of radio frequency and microneedling designed to rapidly remodel and rebuild collagen. You’ll see results after 1 visit, but you will likely require more treatments to tighten your loose skin.
How it works:
Best for: Moderate to significant skin laxity on face, neck, abdomen, arms, thighs, and buttocks.
Radiesse® and Hyperdilute Radiesse® are dual-purpose fillers. They instantly plump thinning areas, but also revitalize collagen production to reduce volume loss and smooth away imperfections. Hyperdilute Radiesse® is thinned out with a combination of saline and lidocaine to boost collagen in areas other than the face.
How it works:
Best for: Volume loss in buttocks, hands, and body areas needing both immediate lift and long-term collagen stimulation.
In addition to being a face volumizer, the poly-L-lactic acid (PLLA) microparticles in Sculptra® stimulate collagen production. All fillers stimulate collagen production, but none more than Sculptra®.
How it works:
Best for: Gradual, natural-looking volume restoration in face, temples, and buttocks (Brazilian Butt Lift alternative).
FORMA Skin Tightening is a surgery, laser, and injection-free anti-aging alternative. It is a pain-free combination of radio frequency and heat that target the dermal layers of the skin, boosting collagen production. Multiple treatments are required.
How it works:
Best for: Mild to moderate skin laxity on face, neck, and body; ideal for maintenance during weight loss.
Platelet-rich plasma utilizes your own blood platelets to inject a plasma-rich concentration back into your body for a variety of benefits. In terms of the visible signs of aging, PRP can regrow healthy tissue and boost collagen production. PRP can also be used for scars, hair loss, enlarged pores, and more.
How it works:
Best for: Skin texture improvement, collagen stimulation, and overall skin rejuvenation on face and body.
Yes! Start skin-supporting treatments early in your weight loss journey. Strength training, adequate protein, hydration, and treatments like Morpheus8 during weight loss can minimize skin laxity.
Skin can continue tightening for up to 2 years after weight loss, but most improvement happens in the first 6-12 months. Younger individuals and those who lost weight more slowly typically see better natural tightening.
Typically no, unless the loose skin causes medical issues like infections or mobility problems. Most treatments are considered cosmetic.
Absolutely! Many individuals combine Morpheus8 with Sculptra® or Radiesse® for comprehensive rejuvenation.
Ideally, start preventive treatments during weight loss and continue after reaching your goal weight. This proactive approach yields the best results.
Many individuals have successfully addressed skin laxity during their weight loss journey. One person shared, “I started Morpheus8 treatments when I’d lost 40 pounds on GLP-1. By the time I reached my goal of 75 pounds lost, my skin looked amazing! No saggy butt or face!”
Another told us, “I was so worried about loose skin after losing 110 pounds. The team at Valley Medical created a plan combining strength training, protein supplements, and Sculptra treatments. I look and feel better than I did 20 years ago!”
Join our newsletter for expert insights on treating melasma, hyperpigmentation, and other skin concerns. Our medical aesthetic team shares practical advice to help you achieve clear, radiant skin.
Valley Medical Weight Loss has been helping individuals achieve their health and wellness goals for over 15 years, with more than 80,000 patients served across the Phoenix metro area. Our four convenient locations in Phoenix, Tempe, Glendale, and Chandler offer physician-supervised weight loss programs, advanced treatments, and personalized support—all with transparent pricing and no hidden fees. We believe in making effective weight loss accessible, affordable, and sustainable for everyone
We havea variety of scientifically proven weight loss options to explore, plus advanced aesthetic treatments to help you look and feel your best throughout your transformation.
Visit us at any location:
Walk-In Hours: Mon, Tue, Thu, Fri: 9am-4:30pm Sat: 8am-1:30pm Wed, Sun: Closed
GLP-1 Weight Loss Options:
Skin Tightening Treatments:
Injectable Treatments:
Weight Loss Programs:
Nutritional Support:
Related Articles:
Additional Resources:
By Dr. Samuel Zuniga, ND
Valley Medical Weight Loss | Chandler, Arizona
The buzz around the weekly weight loss injection Ozempic continues to grow, but a few side effects are causing some to take pause. At the top of this list are Ozempic® butt, Ozempic® face, and Ozempic® body.
If you are taking Ozempic®, Wegovy®, or generic GLP-1 for diabetes or weight loss, the last thing you want is the side effect of loose and wrinkly skin. This rare side effect creates a mix of emotions. The number on the scale is decreasing and clothing fits better, but wrinkly sagging skin can leave you feeling self-conscious.
At Valley Medical Weight Loss and Med Spa across all four Phoenix metro locations, we help individuals prevent and treat skin laxity during rapid weight loss through proactive strategies and advanced aesthetic treatments.
Let’s dive in and discuss what these terms mean, if you are at risk, and what to do if it impacts you.
This refers to the sagging and wrinkled skin that is a rare side effect of any rapid weight loss intervention. Since Ozempic® is more mainstream than other interventions, we hear about it more. However, bariatric surgery patients have the same concern. So do many moms after giving birth and breastfeeding. If you watch shows like The Biggest Loser, it’s something some of the contestants reference.
Where the sagging occurs varies greatly from those it affects, as you can’t pick and choose when, where, and how fast you will lose weight in any area—or if you will develop Ozempic® butt.
Common areas affected:
Through experience at Valley Medical Weight Loss, we’ve observed that proactive treatment during weight loss—not just after—yields the best results for preventing and minimizing skin laxity.
It’s easy to forget, but your skin is your body’s largest organ. It is a protective barrier comprised of proteins, including collagen and elastin.
Collagen and elastin work together to provide your skin’s structure, elasticity, strength, firmness, fullness, moisture, and hydration.
As you gain weight, your skin stretches to accommodate the excess volume. As you lose weight, the skin has less internal tissue to cover. This can make some areas look flat or hollow and can cause sagging.
Unless your collagen and elastin fibers have been damaged, your body can regain much of its elasticity, but it takes time. Either way, the faster you lose weight, the more noticeable the sagging.
In addition to the sagging, skin often looks wrinkly. Since we associate wrinkles with aging, you may feel like you look older than your chronological age. However, the wrinkles caused by Ozempic® butt or body aren’t the same as wrinkles caused by aging or sun exposure.
Think of it a bit more like a deflated balloon. When inflated, the balloon is full and smooth. When deflated it’s smaller than it was before you blew it up but stretched out and wrinkly. The same is true for your skin.
Unlike a balloon, you can actively work to regain elasticity.
There are no guarantees one way or the other, and this side effect is rare. However, there are some factors that will increase the risk of sagging skin.
The more fat you have in any region of your body, the more it increases your odds of sagging. You may have loose skin in several places or just one or two. If you have 100 or more pounds to lose, loose skin is far more likely, but it can occur if you have far less to lose.
The longer you have been obese, the more likely it is that your collagen and elastin have been damaged. Those with 100 or more pounds to lose are at a higher risk for Ozempic® butt or sagging in other areas. However, the longer your skin has been stretched out, the more likely damage has occurred.
As you age, your body produces less collagen and elastin. So even if there is no damage, your skin may not have the regeneration capacity to tighten back up. Women experience accelerated collagen loss during menopause—up to 30% in the first five years.
You’ve likely heard that the sun can prematurely age your skin. This is caused by damaging and slowing down the natural production of collagen and elastin. So, be sure to lather up daily with broad-spectrum UV protection. Reapply every 4 hours when in the sun for extended periods of time. In Arizona’s intense sun, daily SPF 50+ is essential.
How your skin responds to weight loss, and how you age in general, are linked to your individual genetics. There is nothing you can do to change your genetics, but you may be able to stimulate your body’s regeneration process.
Your lifestyle can prematurely age you in a variety of ways. Smoking is at the top of this list as it damages collagen and prematurely slows production. Consistently insufficient sleep and poor overall skincare also contribute to skin health and appearance.
In most cases, Ozempic® butt is primarily a cosmetic concern. However, it can pose some health risks and lifestyle disturbances.
Physical discomfort: Loose skin can get in the way while working out or going about daily life. This may keep you from doing some of the things you love, even things you did before you lost weight.
Mental and emotional: You may worry about other people seeing your loose skin, causing a new body image issue. Although you can fit into smaller clothing, it may limit what you feel comfortable wearing.
Skin conditions: If your skin folds over itself, you are at a higher risk for skin-irritation-related health issues. This includes excessive sweat, fungus, rashes, and ulcers. If not treated promptly these can be painful and lead to severe infections.
Through work at Valley Medical Weight Loss, we provide emotional support and practical solutions to help individuals feel confident throughout their weight loss journey.
Your skin is 80% collagen, so stimulating collagen production may accelerate the rate at which your skin recovers. Even if it isn’t damaged, after drastic weight loss, your collagen is not as strong or healthy as it was before your weight gain.
We take a deep dive into collagen regeneration in this blog post about preventing sagging skin, but below are a few tips to minimize Ozempic® butt:
This includes bone broth, nuts, seeds, legumes, dairy, fish, eggs, chicken, beef, and other foods high in protein. Also, drink plenty of water—aim for 80-100 oz daily for optimal skin hydration.
Key nutrients for collagen:
Consider taking a collagen supplement a few days a week, along with supplements that support collagen or minimize oxidative damage such as vitamin C, zinc, copper, Panax ginseng, omegas, and algae.
Effective supplementation:
Our Pure O.N.E Multivitamin provides many of these essential nutrients for skin health during weight loss.
This includes minimizing alcohol, trans fat, sugar, and caffeine. Also, exercise (especially strength training to build muscle), prioritize quality sleep (7-9 hours nightly), stop smoking, and personalize your whole-body health.
Daily habits that help:
Skip topical collagen creams (molecules are too large to penetrate skin) but apply antioxidant-rich daily moisturizers from head to toe. Don’t forget daily UV protection.
Effective topical ingredients:
Surgery is an option, but it typically isn’t covered by insurance. It also comes with pain and swelling that requires taking a few weeks off from work. If surgery isn’t right for you, there are a variety of non-surgical options to explore.
We will work with you to determine what treatment is appropriate for the area of your body you are experiencing sagging. You may require different treatments for Ozempic® butt and Ozempic® face.
Morpheus8 is a combination of radio frequency and microneedling designed to rapidly remodel and rebuild collagen. You’ll see results after 1 visit, but you will likely require more treatments to tighten your loose skin.
How it works:
Best for: Moderate to significant skin laxity on face, neck, abdomen, arms, thighs, and buttocks.
Radiesse® and Hyperdilute Radiesse® are dual-purpose fillers. They instantly plump thinning areas, but also revitalize collagen production to reduce volume loss and smooth away imperfections. Hyperdilute Radiesse® is thinned out with a combination of saline and lidocaine to boost collagen in areas other than the face.
How it works:
Best for: Volume loss in buttocks, hands, and body areas needing both immediate lift and long-term collagen stimulation.
In addition to being a face volumizer, the poly-L-lactic acid (PLLA) microparticles in Sculptra® stimulate collagen production. All fillers stimulate collagen production, but none more than Sculptra®.
How it works:
Best for: Gradual, natural-looking volume restoration in face, temples, and buttocks (Brazilian Butt Lift alternative).
FORMA Skin Tightening is a surgery, laser, and injection-free anti-aging alternative. It is a pain-free combination of radio frequency and heat that target the dermal layers of the skin, boosting collagen production. Multiple treatments are required.
How it works:
Best for: Mild to moderate skin laxity on face, neck, and body; ideal for maintenance during weight loss.
Platelet-rich plasma utilizes your own blood platelets to inject a plasma-rich concentration back into your body for a variety of benefits. In terms of the visible signs of aging, PRP can regrow healthy tissue and boost collagen production. PRP can also be used for scars, hair loss, enlarged pores, and more.
How it works:
Best for: Skin texture improvement, collagen stimulation, and overall skin rejuvenation on face and body.
Yes! Start skin-supporting treatments early in your weight loss journey. Strength training, adequate protein, hydration, and treatments like Morpheus8 during weight loss can minimize skin laxity.
Skin can continue tightening for up to 2 years after weight loss, but most improvement happens in the first 6-12 months. Younger individuals and those who lost weight more slowly typically see better natural tightening.
Typically no, unless the loose skin causes medical issues like infections or mobility problems. Most treatments are considered cosmetic.
Absolutely! Many individuals combine Morpheus8 with Sculptra® or Radiesse® for comprehensive rejuvenation.
Ideally, start preventive treatments during weight loss and continue after reaching your goal weight. This proactive approach yields the best results.
Many individuals have successfully addressed skin laxity during their weight loss journey. One person shared, “I started Morpheus8 treatments when I’d lost 40 pounds on GLP-1. By the time I reached my goal of 75 pounds lost, my skin looked amazing! No saggy butt or face!”
Another told us, “I was so worried about loose skin after losing 110 pounds. The team at Valley Medical created a plan combining strength training, protein supplements, and Sculptra treatments. I look and feel better than I did 20 years ago!”
Join our newsletter for expert insights on treating melasma, hyperpigmentation, and other skin concerns. Our medical aesthetic team shares practical advice to help you achieve clear, radiant skin.
Valley Medical Weight Loss has been helping individuals achieve their health and wellness goals for over 15 years, with more than 80,000 patients served across the Phoenix metro area. Our four convenient locations in Phoenix, Tempe, Glendale, and Chandler offer physician-supervised weight loss programs, advanced treatments, and personalized support—all with transparent pricing and no hidden fees. We believe in making effective weight loss accessible, affordable, and sustainable for everyone
We havea variety of scientifically proven weight loss options to explore, plus advanced aesthetic treatments to help you look and feel your best throughout your transformation.
Visit us at any location:
Walk-In Hours: Mon, Tue, Thu, Fri: 9am-4:30pm Sat: 8am-1:30pm Wed, Sun: Closed
GLP-1 Weight Loss Options:
Skin Tightening Treatments:
Injectable Treatments:
Weight Loss Programs:
Nutritional Support:
Related Articles:
Additional Resources:
By: The Hidden Epidemic of Sexual Health and What We Can Do
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Monday, Tuesday, Thursday, Friday: 9:00 am-4:30 pm
Saturday: 8am-1:30pm
Wednesday & Sunday: Closed
Med Spa: By appointment only