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Say Goodbye to Crepey Skin!

By: Crepey skin, thin, wrinkled, papery-textured skin that resembles crepe paper, is one of the most frustrating signs of aging. It shows up in places you might not expect: your neck, décolletage, upper arms, hands, knees, and even your abdomen. And unlike fine lines on your face, crepey skin is

crepey skin treatment
Picture of Valley Medical Team

Valley Medical Team

Published:

April 3, 2024

Updated:

April 19, 2026

Published:

April 3, 2024

Updated:

April 19, 2026

Crepey skin, thin, wrinkled, papery-textured skin that resembles crepe paper, is one of the most frustrating signs of aging.

It shows up in places you might not expect: your neck, décolletage, upper arms, hands, knees, and even your abdomen. And unlike fine lines on your face, crepey skin is harder to hide with makeup or clothing.

The good news? You don’t have to live with it.

Hyperdilute Radiesse® is a game-changing treatment that stimulates collagen production in areas beyond the face, giving you smoother, firmer, more youthful-looking skin from head to toe.

Here’s everything you need to know about crepey skin, how Hyperdilute Radiesse® works, and whether it’s the right treatment for you.

What Causes Crepey Skin?

Crepey skin develops when your skin loses collagen, elastin, and moisture, leading to a thin, loose, wrinkled texture.

Common causes include:

  • Aging: Collagen production decreases by ~1% per year starting in your mid-20s
  • Sun exposure: UV rays break down collagen and elastin fibers
  • Weight loss: Rapid or significant weight loss can leave excess, loose skin
  • Pregnancy: Stretched skin on the abdomen may not fully bounce back
  • Dehydration: Chronic dehydration weakens the skin’s structure and elasticity
  • Smoking: Accelerates collagen breakdown and reduces oxygen to the skin
  • Genetics: Some people are more prone to thin, fragile skin

Areas most affected by crepey skin:

  • Neck and jawline
  • Décolletage (chest)
  • Upper arms
  • Hands
  • Knees
  • Abdomen
  • Buttocks and thighs (cellulite)

The bottom line: Crepey skin is caused by collagen loss, and the solution is to stimulate new collagen production.

Get Weekly Aesthetic Tips

Join our newsletter for expert insights on injectables, facial rejuvenation, and the latest aesthetic treatments. Our medical team shares practical advice to help you look and feel your best.

What Is Hyperdilute Radiesse®?

Hyperdilute Radiesse® is a collagen-stimulating injectable designed to treat crepey skin on the body, not just the face.

How It Works

Radiesse® contains calcium hydroxylapatite (CaHA) microspheres suspended in a gel carrier.

When injected into the skin:

  1. The gel provides immediate structure and support
  2. The CaHA microspheres stimulate your body to produce new collagen
  3. Over 4–6 weeks, your skin becomes firmer, smoother, and more elastic
  4. Results continue to improve for up to 3 months as collagen builds

Unlike hyaluronic acid fillers (like Juvéderm®), which plump and hydrate, Radiesse® works by triggering your body’s natural collagen production, leading to longer-lasting, more natural-looking results.

What Makes Hyperdilute Different?

Traditional Radiesse® is FDA-approved for facial wrinkles, folds, and volume loss (nasolabial folds, marionette lines, chin, jawline).

Hyperdilute Radiesse® is the same formula but diluted with saline and lidocaine (a numbing agent). This allows it to be injected into larger body areas where crepey skin is a concern.

Benefits of Hyperdilute Radiesse®:

  • Treats crepey skin on neck, chest, arms, hands, knees, abdomen, buttocks
  • Stimulates collagen production (not just temporary plumping)
  • Results last up to 2 years with annual maintenance
  • Minimal downtime
  • Virtually pain-free (lidocaine is mixed into the formula)

Hyperdilute Radiesse® vs. Other Fillers: What's the Difference?

Not all fillers are created equal. Here’s how Hyperdilute Radiesse® compares to other popular injectables.

Radiesse® vs. Juvéderm®

Radiesse®

Juvéderm®

Calcium hydroxylapatite (CaHA)

Hyaluronic acid (HA)

Stimulates collagen production

Plumps and hydrates skin

Results develop over 4–6 weeks

Results are immediate

Lasts up to 2 years

Lasts 6–24 months (depending on formula)

Best for collagen stimulation and long-term improvement

Best for immediate volume and contouring

The bottom line: Juvéderm® is great for instant plumping (lips, cheeks, under-eye hollows). Radiesse® is better for long-term collagen building and natural-looking firmness.

Radiesse® vs. Sculptra®

Sculptra® is another collagen-stimulating injectable (made from poly-L-lactic acid).

Key differences:

  • Sculptra® requires 2–3 treatment sessions spaced 4–6 weeks apart
  • Radiesse® typically requires 1–2 sessions
  • Both last up to 2 years
  • Both work by stimulating collagen (not immediate plumping)

Your provider can help you decide which collagen stimulator is best for your goals and skin type.

What Areas Can Hyperdilute Radiesse® Treat?

Hyperdilute Radiesse® is FDA-approved for the hands, but it’s commonly used off-label to treat crepey skin on the body.

Neck

The neck ages faster than the face because:

  • Skin is thinner and more delicate
  • We often forget to apply sunscreen and anti-aging products
  • “Tech neck” (looking down at phones) creates deep horizontal lines

Hyperdilute Radiesse® smooths neck wrinkles and tightens loose skin.

Décolletage (Chest)

The skin on your chest is thin, with fewer oil glands, making it prone to:

  • Dryness and irritation
  • Sun damage and age spots
  • Wrinkles and crepey texture

Hyperdilute Radiesse® restores smoothness and firmness to the décolletage

Upper Arms

Loose, sagging skin on the upper arms (often called “bat wings”) is common after weight loss or aging.

Hyperdilute Radiesse® can improve skin firmness, but for moderate to severe laxity, Forma skin tightening or Morpheus8 may be more effective.

Hands

Your hands age faster than your face because:

  • Skin is very thin
  • Hands are constantly exposed to the sun, water, and harsh chemicals
  • Veins and tendons become more visible as volume decreases

Hyperdilute Radiesse® plumps hands, smooths wrinkles, and hides visible veins.

Knees

Repetitive bending and movement can cause the skin around the knees to become loose and wrinkled.

Hyperdilute Radiesse® smooths fine lines and improves skin texture.

Abdomen

After pregnancy or significant weight loss, abdominal skin can become loose and crepey.

Hyperdilute Radiesse® works best for mild laxity. For moderate to severe sagging, Forma or Morpheus8 Body may be better options.

Buttocks and Thighs (Cellulite)

80–90% of women have cellulite (compared to ~10% of men). Cellulite is caused by connective tissue pulling down on the skin, creating a dimpled appearance.

Hyperdilute Radiesse® can fill in dimples and smooth skin texture, but it’s not a cure for cellulite. Combining treatments (Radiesse® + Morpheus8 Body) often delivers the best results.

What to Expect: Treatment, Downtime, and Results

How Long Does Treatment Take?

60–90 minutes for most areas. Larger areas (abdomen, thighs) may take longer.

You may need 1–2 sessions spaced 4–6 weeks apart for optimal results.

Does It Hurt?

Hyperdilute Radiesse® contains lidocaine (a numbing agent), so most patients report minimal discomfort.

For extra comfort, we offer Pro-Nox (nitrous oxide, or “laughing gas”), the same thing used at the dentist. It wears off quickly, so you can drive yourself home.

What’s the Downtime?

Minimal. Most patients return to work and normal activities the same day.

Common side effects (temporary, 3–7 days):

  • Mild swelling
  • Bruising
  • Redness
  • Tenderness at injection sites

Post-treatment tips:

  • Avoid strenuous exercise for 24–48 hours
  • Avoid direct sun exposure for 48 hours
  • Apply ice packs to reduce swelling
  • Take Tylenol (not ibuprofen or aspirin) for discomfort

When Will I See Results?

  • Initial results: 1 week
  • Full results: 4–6 weeks (as collagen builds)
  • Results last: Up to 2 years
  • Maintenance: Every 12 months

Is Hyperdilute Radiesse® Safe?

Yes, when performed by a licensed, experienced provider.

Radiesse® is FDA-approved and has been used safely for over 20 years.

Important Safety Warning:

Never Use At-Home or DIY Fillers

At-home fillers are NOT FDA-approved. Many contain silicone, which can cause:

  • Infection
  • Scarring
  • Disfigurement
  • Silicone embolism (blockage of blood vessels in the brain, lungs, or heart)
  • Stroke or death

Silicone can only be removed surgically, and the damage is often permanent.

Only use FDA-approved fillers administered by licensed medical professionals.

Is Hyperdilute Radiesse® Right for You?

Hyperdilute Radiesse® is ideal if you:

  • Have mild to moderate crepey skin on your neck, chest, arms, hands, or body
  • Want long-lasting results (up to 2 years)
  • Prefer a collagen-stimulating treatment (not just temporary plumping)
  • Want minimal downtime

You may need a different treatment if:

  • You have severe skin laxity (Forma or Morpheus8 may be better)
  • You want immediate results (Juvéderm® or Sculptra® may be better)
  • You’re pregnant, breastfeeding, or have certain medical conditions (discuss with your provider)

Not sure which treatment is right for you? Schedule a consultation at Valley Medical Weight Loss. We’ll assess your skin, discuss your goals, and create a personalized treatment plan.

Ready to Say Goodbye to Crepey Skin?

Hyperdilute Radiesse® is a safe, effective, long-lasting solution for crepey skin on the body.

Schedule a consultation at Valley Medical Weight Loss to discuss your options and create a personalized treatment plan.

Contact us to get started

About Valley Medical Weight Loss

For over 15 years, Valley Medical Weight Loss has helped more than 80,000 patients achieve their weight loss and aesthetic goals with personalized, physician-supervised programs. We offer transparent pricing, no-contract plans, and walk-in convenience at four Phoenix-area locations.

Learn more about Valley Medical Weight Loss

Important Information

General Disclaimer: This article is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider before starting new treatments, especially if you are pregnant, breastfeeding, or have medical conditions.

Aesthetic Treatment Disclaimer: Individual results may vary. All aesthetic treatments are performed by licensed medical professionals. A consultation is required to determine if you are a candidate for treatment. Radiesse® is FDA-approved for hand rejuvenation; other uses are off-label.

More Resources

Aesthetic Treatments:

Say Goodbye to Crepey Skin!

By Dr. Samuel Zuniga, ND
Valley Medical Weight Loss | Chandler, Arizona

Crepey skin, thin, wrinkled, papery-textured skin that resembles crepe paper, is one of the most frustrating signs of aging.

It shows up in places you might not expect: your neck, décolletage, upper arms, hands, knees, and even your abdomen. And unlike fine lines on your face, crepey skin is harder to hide with makeup or clothing.

The good news? You don’t have to live with it.

Hyperdilute Radiesse® is a game-changing treatment that stimulates collagen production in areas beyond the face, giving you smoother, firmer, more youthful-looking skin from head to toe.

Here’s everything you need to know about crepey skin, how Hyperdilute Radiesse® works, and whether it’s the right treatment for you.

What Causes Crepey Skin?

Crepey skin develops when your skin loses collagen, elastin, and moisture, leading to a thin, loose, wrinkled texture.

Common causes include:

  • Aging: Collagen production decreases by ~1% per year starting in your mid-20s
  • Sun exposure: UV rays break down collagen and elastin fibers
  • Weight loss: Rapid or significant weight loss can leave excess, loose skin
  • Pregnancy: Stretched skin on the abdomen may not fully bounce back
  • Dehydration: Chronic dehydration weakens the skin’s structure and elasticity
  • Smoking: Accelerates collagen breakdown and reduces oxygen to the skin
  • Genetics: Some people are more prone to thin, fragile skin

Areas most affected by crepey skin:

  • Neck and jawline
  • Décolletage (chest)
  • Upper arms
  • Hands
  • Knees
  • Abdomen
  • Buttocks and thighs (cellulite)

The bottom line: Crepey skin is caused by collagen loss, and the solution is to stimulate new collagen production.

Get Weekly Aesthetic Tips

Join our newsletter for expert insights on injectables, facial rejuvenation, and the latest aesthetic treatments. Our medical team shares practical advice to help you look and feel your best.

What Is Hyperdilute Radiesse®?

Hyperdilute Radiesse® is a collagen-stimulating injectable designed to treat crepey skin on the body, not just the face.

How It Works

Radiesse® contains calcium hydroxylapatite (CaHA) microspheres suspended in a gel carrier.

When injected into the skin:

  1. The gel provides immediate structure and support
  2. The CaHA microspheres stimulate your body to produce new collagen
  3. Over 4–6 weeks, your skin becomes firmer, smoother, and more elastic
  4. Results continue to improve for up to 3 months as collagen builds

Unlike hyaluronic acid fillers (like Juvéderm®), which plump and hydrate, Radiesse® works by triggering your body’s natural collagen production, leading to longer-lasting, more natural-looking results.

What Makes Hyperdilute Different?

Traditional Radiesse® is FDA-approved for facial wrinkles, folds, and volume loss (nasolabial folds, marionette lines, chin, jawline).

Hyperdilute Radiesse® is the same formula but diluted with saline and lidocaine (a numbing agent). This allows it to be injected into larger body areas where crepey skin is a concern.

Benefits of Hyperdilute Radiesse®:

  • Treats crepey skin on neck, chest, arms, hands, knees, abdomen, buttocks
  • Stimulates collagen production (not just temporary plumping)
  • Results last up to 2 years with annual maintenance
  • Minimal downtime
  • Virtually pain-free (lidocaine is mixed into the formula)

Hyperdilute Radiesse® vs. Other Fillers: What's the Difference?

Not all fillers are created equal. Here’s how Hyperdilute Radiesse® compares to other popular injectables.

Radiesse® vs. Juvéderm®

Radiesse®

Juvéderm®

Calcium hydroxylapatite (CaHA)

Hyaluronic acid (HA)

Stimulates collagen production

Plumps and hydrates skin

Results develop over 4–6 weeks

Results are immediate

Lasts up to 2 years

Lasts 6–24 months (depending on formula)

Best for collagen stimulation and long-term improvement

Best for immediate volume and contouring

The bottom line: Juvéderm® is great for instant plumping (lips, cheeks, under-eye hollows). Radiesse® is better for long-term collagen building and natural-looking firmness.

Radiesse® vs. Sculptra®

Sculptra® is another collagen-stimulating injectable (made from poly-L-lactic acid).

Key differences:

  • Sculptra® requires 2–3 treatment sessions spaced 4–6 weeks apart
  • Radiesse® typically requires 1–2 sessions
  • Both last up to 2 years
  • Both work by stimulating collagen (not immediate plumping)

Your provider can help you decide which collagen stimulator is best for your goals and skin type.

What Areas Can Hyperdilute Radiesse® Treat?

Hyperdilute Radiesse® is FDA-approved for the hands, but it’s commonly used off-label to treat crepey skin on the body.

Neck

The neck ages faster than the face because:

  • Skin is thinner and more delicate
  • We often forget to apply sunscreen and anti-aging products
  • “Tech neck” (looking down at phones) creates deep horizontal lines

Hyperdilute Radiesse® smooths neck wrinkles and tightens loose skin.

Décolletage (Chest)

The skin on your chest is thin, with fewer oil glands, making it prone to:

  • Dryness and irritation
  • Sun damage and age spots
  • Wrinkles and crepey texture

Hyperdilute Radiesse® restores smoothness and firmness to the décolletage

Upper Arms

Loose, sagging skin on the upper arms (often called “bat wings”) is common after weight loss or aging.

Hyperdilute Radiesse® can improve skin firmness, but for moderate to severe laxity, Forma skin tightening or Morpheus8 may be more effective.

Hands

Your hands age faster than your face because:

  • Skin is very thin
  • Hands are constantly exposed to the sun, water, and harsh chemicals
  • Veins and tendons become more visible as volume decreases

Hyperdilute Radiesse® plumps hands, smooths wrinkles, and hides visible veins.

Knees

Repetitive bending and movement can cause the skin around the knees to become loose and wrinkled.

Hyperdilute Radiesse® smooths fine lines and improves skin texture.

Abdomen

After pregnancy or significant weight loss, abdominal skin can become loose and crepey.

Hyperdilute Radiesse® works best for mild laxity. For moderate to severe sagging, Forma or Morpheus8 Body may be better options.

Buttocks and Thighs (Cellulite)

80–90% of women have cellulite (compared to ~10% of men). Cellulite is caused by connective tissue pulling down on the skin, creating a dimpled appearance.

Hyperdilute Radiesse® can fill in dimples and smooth skin texture, but it’s not a cure for cellulite. Combining treatments (Radiesse® + Morpheus8 Body) often delivers the best results.

What to Expect: Treatment, Downtime, and Results

How Long Does Treatment Take?

60–90 minutes for most areas. Larger areas (abdomen, thighs) may take longer.

You may need 1–2 sessions spaced 4–6 weeks apart for optimal results.

Does It Hurt?

Hyperdilute Radiesse® contains lidocaine (a numbing agent), so most patients report minimal discomfort.

For extra comfort, we offer Pro-Nox (nitrous oxide, or “laughing gas”), the same thing used at the dentist. It wears off quickly, so you can drive yourself home.

What’s the Downtime?

Minimal. Most patients return to work and normal activities the same day.

Common side effects (temporary, 3–7 days):

  • Mild swelling
  • Bruising
  • Redness
  • Tenderness at injection sites

Post-treatment tips:

  • Avoid strenuous exercise for 24–48 hours
  • Avoid direct sun exposure for 48 hours
  • Apply ice packs to reduce swelling
  • Take Tylenol (not ibuprofen or aspirin) for discomfort

When Will I See Results?

  • Initial results: 1 week
  • Full results: 4–6 weeks (as collagen builds)
  • Results last: Up to 2 years
  • Maintenance: Every 12 months

Is Hyperdilute Radiesse® Safe?

Yes, when performed by a licensed, experienced provider.

Radiesse® is FDA-approved and has been used safely for over 20 years.

Important Safety Warning:

Never Use At-Home or DIY Fillers

At-home fillers are NOT FDA-approved. Many contain silicone, which can cause:

  • Infection
  • Scarring
  • Disfigurement
  • Silicone embolism (blockage of blood vessels in the brain, lungs, or heart)
  • Stroke or death

Silicone can only be removed surgically, and the damage is often permanent.

Only use FDA-approved fillers administered by licensed medical professionals.

Is Hyperdilute Radiesse® Right for You?

Hyperdilute Radiesse® is ideal if you:

  • Have mild to moderate crepey skin on your neck, chest, arms, hands, or body
  • Want long-lasting results (up to 2 years)
  • Prefer a collagen-stimulating treatment (not just temporary plumping)
  • Want minimal downtime

You may need a different treatment if:

  • You have severe skin laxity (Forma or Morpheus8 may be better)
  • You want immediate results (Juvéderm® or Sculptra® may be better)
  • You’re pregnant, breastfeeding, or have certain medical conditions (discuss with your provider)

Not sure which treatment is right for you? Schedule a consultation at Valley Medical Weight Loss. We’ll assess your skin, discuss your goals, and create a personalized treatment plan.

Ready to Say Goodbye to Crepey Skin?

Hyperdilute Radiesse® is a safe, effective, long-lasting solution for crepey skin on the body.

Schedule a consultation at Valley Medical Weight Loss to discuss your options and create a personalized treatment plan.

Contact us to get started

About Valley Medical Weight Loss

For over 15 years, Valley Medical Weight Loss has helped more than 80,000 patients achieve their weight loss and aesthetic goals with personalized, physician-supervised programs. We offer transparent pricing, no-contract plans, and walk-in convenience at four Phoenix-area locations.

Learn more about Valley Medical Weight Loss

Important Information

General Disclaimer: This article is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider before starting new treatments, especially if you are pregnant, breastfeeding, or have medical conditions.

Aesthetic Treatment Disclaimer: Individual results may vary. All aesthetic treatments are performed by licensed medical professionals. A consultation is required to determine if you are a candidate for treatment. Radiesse® is FDA-approved for hand rejuvenation; other uses are off-label.

More Resources

Aesthetic Treatments:

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I’ve had a great experience working with Valley Medical in Chandler. I have lost 20 pounds so far with the help from Alejandra, she has been very informative on this journey. Everyone here is very friendly and personable. If you are looking to lose weight and have more energy I would highly recommend coming to start your journey!
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Love it here ! Friendly, fast and makes me feel motivated ! Christine and Amelia were phenomenal slay queens ! I've lost 5ibs since being here ! I'm ready to keep going 🩵
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Alejandra was fantastic one of the best workers up in the office had a great and uplifting attitude she went above and beyond to help answers all questions efficiently would highly recommend goin here 12 out of 10 ratings great job
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I highly recommend Valley Medical Weight Loss! Alejandra has been amazing from day one supportive, motivating, and truly invested in my success. In just over 8 weeks, I’ve lost nearly 30 pounds. They genuinely care about your health and make the process feel manageable and personalized. Thank you, Alejandra!
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Awesome staff, courteous and clean. I’m down 40 lbs in one month. Prices for supplements are better than getting them from Amazon!
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I’ve had a great experience here so far. The staff is absolutely amazing very kind, supportive, and always willing to answer my questions. They truly make you feel comfortable and encouraged throughout the weight-loss process. I’m seeing results and feel well taken care of. Highly recommend!
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Love the new clinic, the space is beautiful and welcoming, and the staff was amazing! Alejandra took great care of me. She was very informative, made me feel comfortable throughout the whole process, and I honestly didn’t even feel my injection. Such a great experience, and I’m already looking forward to coming back!
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